[00:00]
SUPERS:[EBGLYSS logo]
[00:05]
SUPERS:[EBGLYSS logo]
Getting Started with EBGLYSS
INDICATION
EBGLYSS is a prescription medicine used to treat adults and children 12 years of age and older who weigh at least 88 pounds (40kg) with moderate-to-severe eczema (atopic dermatitis) that is not well controlled with prescription therapies used on the skin (topical), or who cannot use topical therapies. EBGLYSS can be used with or without topical corticosteroids.
It is not known if EBGLYSS is safe and effective in children less than 12 years of age or in children 12 years to less than 18 years of age who weigh less than 88 pounds (40 kg).
SELECT IMPORTANT SAFETY INFORMATIONDo not use EBGLYSS if you are allergic to lebrikizumab-lbkz or to any of the ingredients in EBGLYSS. See the Patient Information leaflet that comes with EBGLYSS for a complete list of ingredients.
VO/SUPERS:
Please see Indication and Safety Summary at the end of this video.
Please see the Instructions for Use included with your device.[00:31]
AUDIO:Doctor: So Alex, EBGLYSS marks a new chapter in you managing your moderate-to-severe eczema.
Current Alex: Okay, thank you so much, doc! I’ll be sure to reach out if I have any questions about EBGLYSS.
Doctor: Please do, we’re here for you anytime.
Current Alex: Great.
Doctor: Take care.
Current Alex: Thank you.
SUPERS/GRAPHICS:[EBGLYSS logo]
Actor portrayals.
[01:00]
AUDIO:Future Alex: Hi!
[01:01]
AUDIO:Current Alex: Hi. What is going on?
[01:07]
AUDIO:Future Alex: I’m just gonna…
[01:13]
AUDIO:Future Alex: I’m you from the not-too-distant future.
[01:17]
AUDIO:Future Alex: While your doctor’s always available to help you out, I thought I’d come to help guide you through your?–my?– our EBGLYSS journey.
[01:27]
AUDIO:Current Alex: Okay, this is new. Wait, guide me through what exactly?
Future Alex: Through the initial uncertainties of starting a new treatment.
[01:36]
AUDIO:Future Alex: I know you have a handful of questions, mhmm? And we can talk more about it at home.
[01:43]
AUDIO: Future Alex: Ready to roll?
Current Alex: Sure.
Future Alex: Yeah!
[01:48]
AUDIO:Current Alex: You wouldn’t want to, say, give me some lottery numbers from the future or something, would you?
Future Alex: Nope.
Current Alex: Okay, you’re just here to help me get the hang of EBGLYSS?
[01:54]
AUDIO:Future Alex: Exactly. But seriously, you know how we’re frequently reaching for creams and topicals…
SUPERS/GRAPHICS:[EBGLYSS logo]
[01:58]
AUDIO:Future Alex: …whenever we flare?
SUPERS/GRAPHICS:[EBGLYSS logo]
[02:06]
AUDIO:Current Alex: I remember.
[02:08]
AUDIO:Future Alex: Well, the doctor did tell us that eczema is a long-term condition, but those topicals may only offer short-term relief.
[02:14]
AUDIO:Future Alex: EBGLYSS, on the other hand, works from inside the body.
[02:20]
AUDIO:Future Alex: And when you take it as directed, it works around the clock to target a main source of inflammation that can lead to our dry, itchy, irritated skin.
SUPERS/GRAPHICS:[EBGLYSS logo]
[Dosing graphic with initial dosing]
Please see the full dosing schedule and guidelines at: https://ebglyss.lilly.com/taking-ebglyssPlease see Indication and Safety Summary at the end of this video.
Please see the Instructions for Use included with your device.[02:25]
AUDIO:Future Alex: And after four months of taking it every two weeks, you and the doc can discuss switching to once-monthly dosing.
SUPERS/GRAPHICS:[EBGLYSS logo]
[Dosing graphic with initial dosing and once-monthly dosing]
Please see the full dosing schedule and guidelines at: https://ebglyss.lilly.com/taking-ebglyssPlease see Indication and Safety Summary at the end of this video.
Please see the Instructions for Use included with your device.[02:31]
AUDIO:Current Alex: Oh yeah, the doc mentioned once-monthly maintenance dosing. Yeah, it sounds…
SUPERS/GRAPHICS:[EBGLYSS logo]
[02:35]
AUDIO:Current Alex: …doable.
Future Alex: Exactly.
SUPERS/GRAPHICS:[EBGLYSS logo]
[02:37]
AUDIO:Future Alex: At first, I wasn’t sure how EBGLYSS would fit into my life, but it fit right into my routine.
SUPERS/GRAPHICS:[EBGLYSS logo]
[02:45]
AUDIO:Future Alex: On each dose day, you’ll take EBGLYSS out of the fridge, set a timer for 45 minutes to allow it to get to room temperature, and just go on with your day until it’s ready.
SUPERS/GRAPHICS:[EBGLYSS logo]
Store your device in the refrigerator between 36°F to 46°F (2°C to 8°C). Do not warm up with a microwave, hot water, or sunlight. Do not use if medicine is frozen.
[02:54]
AUDIO:Future Alex: Mornings seem to work best for our schedule, but if you find it works best at some other time, that works, too.
SUPERS/GRAPHICS:[EBGLYSS logo]
[03:01]
AUDIO:Current Alex: One of the parts that makes me a little bit nervous is the self-injections. Do you feel like that was tough to get the hang of?
SUPERS/GRAPHICS:[EBGLYSS logo]
Your healthcare provider should show you how to prepare and inject EBGLYSS. Do not inject yourself or someone else until you have been shown how to inject EBGLYSS.
These are not the complete Instructions for Use. Please see the Instructions for Use included with your device.
[03:06]
AUDIO:Future Alex: I know how you feel, but I did get the hang of it.
SUPERS/GRAPHICS:[EBGLYSS logo]
Your healthcare provider should show you how to prepare and inject EBGLYSS. Do not inject yourself or someone else until you have been shown how to inject EBGLYSS.
These are not the complete Instructions for Use. Please see the Instructions for Use included with your device.
[03:10]
AUDIO:Future Alex: EBGLYSS offers helpful support with virtual one-on-one training from a registered nurse,
SUPERS/GRAPHICS:[EBGLYSS logo]
[03:17]
AUDIO:Future Alex: … these step-by-step videos to get you prepped,
SUPERS/GRAPHICS:[EBGLYSS logo]
Watch at
ebglyss.lilly.com/how-to-inject[03:20]
AUDIO:Future Alex: …and of course, the Instructions for Use that come with the device. It really made a difference for me when I first started.
SUPERS/GRAPHICS:[EBGLYSS logo]
[03:26]
AUDIO:Current Alex: Oh yeah, our doctor mentioned something about Lilly Support Services. What is that?
SUPERS/GRAPHICS:[Lilly Support Services Logo]
[03:30]
AUDIO:Future Alex: Yes! Lilly Support Services for EBGLYSS is a personalized patient support program that’s got our back through the whole treatment process. Once enrolled, you’ll be introduced to your Companion in Care representative, who can help answer questions and provide personalized support…
SUPERS/GRAPHICS:[Lilly Support Services Logo]
HOW TO ENROLL[icon]
TEXT ‘EBS’ to 85099
[icon]
VISIT the Savings & Support page at
ebglyss.lilly.com[icon]
CALL 1-800-LillyRx(
1-800-545-5979) from Monday to Friday between 8 AM and 10 PM ET
Companion in Care™ does not provide medical advice.
[03:48]
AUDIO:Future Alex: …along the whole treatment journey. And if you request it, they’ll even send you a container you can use to safely throw out your used injection devices.
[03:56]
AUDIO:Current Alex: Honestly, I’m feeling a lot less overwhelmed now. But is there a cost to enroll?
[04:02]
AUDIO:Future Alex: Nope. It’s free.
Current Alex: Free?
Future Alex: It’s free.
[04:05]
AUDIO:Current Alex: Free?
[04:06]
AUDIO:Future Alex: It’s free.
[04:07]
AUDIO:Current Alex: Okay!
[04:08]
AUDIO:Future Alex: With Lilly Support Services by our side, we’re pretty well set up. It’s all about making us feel supported.
SUPERS/GRAPHICS:Talk to your healthcare provider about enrolling you in Lilly Support Services.
[04:14]
AUDIO:Current Alex: You’re great.
[04:15]
AUDIO:Future Alex: You’re great.
Future Alex and Current Alex (together): We’re great.
[04:17]
AUDIO:Current Alex: Huh, it’s really all making sense to me now.
Future Alex: I always knew it would.
[04:23]
AUDIO:Future Alex: So I guess my work here is done. But before I go, since we tackled this, what’s the first thing you’re planning to do?
[04:31]
AUDIO:Current Alex: Okay, I’ll revisit my injection and dosing resources, make sure I’ve got all that down, and I will make sure to enroll in…
[04:36]
AUDIO:Current Alex: …Lilly Support Services.
[04:38]
AUDIO:Current Alex: Sounds like something I could really use to help me stay on track.
[04:41]
AUDIO:Future Alex: Smart move. And remember, our doctor and Lilly Support Services are always here if you need any more help. And if I’m this knowledgeable about EBGLYSS in the not-so-distant future, I think you’ll…
[04:54]
AUDIO:Future Alex: …get it too.
SUPERS/GRAPHICS:Please see Indication and Safety Summary at the end of this video.
Please see the Instructions for Use included with your device.For more information, please visit
ebglyss.lilly.com.
[05:02]
SUPERS/GRAPHICS:Please see Indication and Safety Summary at the end of this video.
Please see the Instructions for Use included with your device.For more information, please visit
ebglyss.lilly.com.
[EBGLYSS logo]
[05:11]
AUDIO VO:
INDICATION AND SAFETY SUMMARY
EBGLYSS is an injectable medicine used to treat adults and children 12 years of age and older who weigh at least 88 pounds, or 40 kilograms, with moderate-to-severe eczema, also called atopic dermatitis, that is not well controlled with prescription therapies used on the skin, or topical, or who cannot use topical therapies. EBGLYSS can be used with or without topical corticosteroids.
It is not known if EBGLYSS is safe and effective in children less than 12 years of age or in children 12 years to less than 18 years of age who weigh less than 88 pounds, or 40 kilograms.
WARNINGS - Do not use EBGLYSS if you are allergic to lebrikizumab-lbkz or to any of the ingredients in EBGLYSS. See the Patient Information leaflet that comes with EBGLYSS for a complete list of ingredients.
BEFORE USING
Before using EBGLYSS, tell your healthcare provider about all your medical conditions, including if you:
- Have a parasitic (or helminth) infection.
- Are scheduled to receive any vaccinations. You should not receive a “live vaccine” if you are treated with EBGLYSS.
- Are pregnant or plan to become pregnant. It is not known if EBGLYSS will harm your unborn baby. If you become pregnant during treatment with EBGLYSS, you or your healthcare provider can call Eli Lilly and Company at 1-800-LillyRx (1-800-545-5979) to report the pregnancy.
- Are breastfeeding or plan to breastfeed. It is not known if EBGLYSS passes into your breast milk.
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
POSSIBLE SIDE EFFECTS
EBGLYSS can cause serious side effects, including:
- Allergic reactions. EBGLYSS can cause allergic reactions that may sometimes be severe. Stop using EBGLYSS and tell your healthcare provider or get emergency help right away if you get any of the following signs or symptoms:
- breathing problems or wheezing
- swelling of the face, lips, mouth, tongue or throat
- hives
- itching
- fainting, dizziness, feeling lightheaded
- skin rash
- cramps in your stomach area (or abdomen)
- Eye problems. Tell your healthcare provider if you have any new or worsening eye problems, including eye pain or changes in vision, such as blurred vision.
The most common side effects of EBGLYSS include:
- eye and eyelid inflammation, including redness, swelling, and itching
- injection site reactions
- shingles (herpes zoster)
These are not all of the possible side effects of EBGLYSS. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.
HOW TO TAKE
- See the detailed “Instructions for Use” that come with EBGLYSS for information about how to prepare and inject EBGLYSS and how to properly store and throw away (or dispose of) used EBGLYSS prefilled pens and prefilled syringes.
- Use EBGLYSS exactly as prescribed by your healthcare provider.
- EBGLYSS is given as an injection under the skin (or subcutaneous injection).
- If your healthcare provider decides that you or a caregiver can give the injections of EBGLYSS, you or a caregiver should receive training on the right way to prepare and inject EBGLYSS. Do not try to inject EBGLYSS until you have been shown the right way by your healthcare provider. In children 12 years of age and older, EBGLYSS should be given by a caregiver.
- If you miss a dose of EBGLYSS, inject the missed dose as soon as possible, then inject your next dose at your regular scheduled time.
LEARN MORE
EBGLYSS is a prescription medicine available as a 250 mg per 2 mL injection prefilled pen or prefilled syringe. For more information, call 1-800-545-5979 or go to ebglyss.lilly.com
This summary provides basic information about EBGLYSS but does not include all information known about this medicine. Read the information that comes with your prescription each time your prescription is filled. This information does not take the place of talking to your doctor. Be sure to talk to your doctor or other healthcare provider about EBGLYSS and how to take it. Your doctor is the best person to help you decide if EBGLYSS is right for you.
SUPERS/GRAPHICS:
INDICATION AND SAFETY SUMMARY
EBGLYSS™ (EHB-glihs) is an injectable medicine used to treat adults and children 12 years of age and older who weigh at least 88 pounds (40 kg) with moderate-to-severe eczema (atopic dermatitis) that is not well controlled with prescription therapies used on the skin (topical), or who cannot use topical therapies. EBGLYSS can be used with or without topical corticosteroids.
It is not known if EBGLYSS is safe and effective in children less than 12 years of age or in children 12 years to less than 18 years of age who weigh less than 88 pounds (40 kg).
WARNINGS - Do not use EBGLYSS if you are allergic to lebrikizumab-lbkz or to any of the ingredients in EBGLYSS. See the Patient Information leaflet that comes with EBGLYSS for a complete list of ingredients.
BEFORE USING
Before using EBGLYSS, tell your healthcare provider about all your medical conditions, including if you:- Have a parasitic (helminth) infection.
- Are scheduled to receive any vaccinations. You should not receive a “live vaccine” if you are treated with EBGLYSS.
- Are pregnant or plan to become pregnant. It is not known if EBGLYSS will harm your unborn baby. If you become pregnant during treatment with EBGLYSS, you or your healthcare provider can call Eli Lilly and Company at 1-800-LillyRx (1-800-545-5979) to report the pregnancy.
- Are breastfeeding or plan to breastfeed. It is not known if EBGLYSS passes into your breast milk.
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
POSSIBLE SIDE EFFECTS
EBGLYSS can cause serious side effects, including:- Allergic reactions. EBGLYSS can cause allergic reactions that may sometimes be severe. Stop using EBGLYSS and tell your healthcare provider or get emergency help right away if you get any of the following signs or symptoms:
- breathing problems or wheezing
- swelling of the face, lips, mouth, tongue or throat
- hives
- itching
- fainting, dizziness, feeling lightheaded
- skin rash
- cramps in your stomach area (abdomen)
- Eye problems. Tell your healthcare provider if you have any new or worsening eye problems, including eye pain or changes in vision, such as blurred vision.
The most common side effects of EBGLYSS include:
- eye and eyelid inflammation, including redness, swelling, and itching
- injection site reactions
- shingles (herpes zoster)
These are not all of the possible side effects of EBGLYSS. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.
HOW TO TAKE
- See the detailed “Instructions for Use” that comes with EBGLYSS for information about how to prepare and inject EBGLYSS and how to properly store and throw away (dispose of) used EBGLYSS prefilled pens and prefilled syringes.
- Use EBGLYSS exactly as prescribed by your healthcare provider.
- EBGLYSS is given as an injection under the skin (subcutaneous injection).
- If your healthcare provider decides that you or a caregiver can give the injections of EBGLYSS, you or a caregiver should receive training on the right way to prepare and inject EBGLYSS. Do not try to inject EBGLYSS until you have been shown the right way by your healthcare provider. In children 12 years of age and older, EBGLYSS should be given by a caregiver.
- If you miss a dose of EBGLYSS, inject the missed dose as soon as possible, then inject your next dose at your regular scheduled time.
LEARN MORE
EBGLYSS is a prescription medicine available as a 250 mg/2 mL injection prefilled pen or prefilled syringe. For more information, call 1-800-545-5979 or go to ebglyss.lilly.com
This summary provides basic information about EBGLYSS but does not include all information known about this medicine. Read the information that comes with your prescription each time your prescription is filled. This information does not take the place of talking to your doctor. Be sure to talk to your doctor or other healthcare provider about EBGLYSS and how to take it. Your doctor is the best person to help you decide if EBGLYSS is right for you.
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EBGLYSS™, its delivery device base, Lilly Support Services™, and Companion in Care™ are trademarks owned or licensed by Eli Lilly and Company, its subsidiaries, or affiliates.
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[EBGLYSS logo]